Don't use that ECU tune with those injectors. If it is tuned to run 650cc injectors, and you just stick it in with some 450's, then you will need to increase all your fuel trims, especially under boost or you could run into a dangerously lean condition. The 650's flow alot more so they can use alot shorter pulse width to get the same fuel a 450 would under longer pulse widths
AFC's and VAFC suck as well. They intercept your airflow sensor signal and modify it to trick your ECU into putting more fuel in. When doing this, the ECU goes to a different part of the fuel/ignition timing table to get the required amount of fuel that the airflow sensor requests which causes it to also modify your ignition timing in the process. If I was to get an AFC, I would definitely want an ignition timing controller........but for the price of getting both of those.........Just get Hondata!