Technically yes, but look at it this way.
You will make more power with less boost with high compression
you will make the same power with less compression and more boost
Its a give or take thing.
What Ive learned is, build the car to how it will suit you best, and by that I mean, if your car is seeing 90% of city driving, dont put a large laggy turbo on it or 8:1 compression pistons. you are only making it worse off for yourself in terms of driveability.
10:1,10.5:1 I dont see there being an issue with, I mean people out there are boosting stock S2000's and those have 11.5:1 CR ratios. The owner of full blown motorsports in apple valley MN made 800+whp stock engine s2k last year. MONSTER